Plasma cell survival in the absence of B cell memory
The long-term maintenance of antibody-secreting plasma cells and the requirement for memory B cells are unclear. Here, the authors show that plasma cells and the antibodies secreted are long-lived and maintained over a decade in the absence of memory B cells in non-human primates.
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01901-w |