Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscle.

Adequate levels of physical activity are at the center of a healthy lifestyle. However, the molecular mechanisms that mediate the beneficial effects of exercise remain enigmatic. This gap in knowledge is caused by the lack of an amenable experimental model system. Therefore, we optimized electric pu...

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Bibliographic Details
Main Authors: Nathalie Burch, Anne-Sophie Arnold, Flurin Item, Serge Summermatter, Gesa Brochmann Santana Santos, Martine Christe, Urs Boutellier, Marco Toigo, Christoph Handschin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2881042?pdf=render