Pathway-based Analysis of the Hidden Genetic Heterogeneities in Cancers

Pathway-based Analysis of the Hidden Genetic Heterogeneities in Cancers

Many cancers apparently showing similar phenotypes are actually distinct at the molecular level, leading to very different responses to the same treatment. It has been recently demonstrated that pathway-based approaches are robust and reliable for genetic analysis of cancers. Nevertheless, it remain...

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Bibliographic Details
Main Authors: Xiaolei Zhao, Shouqiang Zhong, Xiaoyu Zuo, Meihua Lin, Jiheng Qin, Yizhao Luan, Naizun Zhang, Yan Liang, Shaoqi Rao
Format: Article
Language:English
Published: Elsevier 2014-02-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Genetic heterogeneity
Pathway-based approach
Sample partitioning
Enrichment analysis
Survival analysis
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022914000023

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http://www.sciencedirect.com/science/article/pii/S1672022914000023

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