Cofilin dysregulation alters actin turnover in frataxin-deficient neurons
Abstract Abnormalities in actin cytoskeleton have been linked to Friedreich’s ataxia (FRDA), an inherited peripheral neuropathy characterised by an early loss of neurons in dorsal root ganglia (DRG) among other clinical symptoms. Despite all efforts to date, we still do not fully understand the mole...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2020-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-020-62050-7 |