Molecular evolution of a-kinase anchoring protein (AKAP)-7: implications in comparative PKA compartmentalization

<p>Abstract</p> <p>Background</p> <p>A-Kinase Anchoring Proteins (AKAPs) are molecular scaffolding proteins mediating the assembly of multi-protein complexes containing cAMP-dependent protein kinase A (PKA), directing the kinase in discrete subcellular locations. Splice...

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Bibliographic Details
Main Authors: Johnson Keven R, Nicodemus-Johnson Jessie, Carnegie Graeme K, Danziger Robert S
Format: Article
Language:English
Published: BMC 2012-07-01
Series:BMC Evolutionary Biology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2148/12/125