FATS is a transcriptional target of p53 and associated with antitumor activity

<p>Abstract</p> <p>Frequent mutations of p53 in human cancers exemplify its crucial role as a tumor suppressor transcription factor, and p21, a transcriptional target of p53, plays a central role in surveillance of cell-cycle checkpoints. Our previous study has shown that FATS stab...

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Bibliographic Details
Main Authors: Zhang Xifeng, Zhang Qian, Zhang Jun, Qiu Li, Yan Shuang-shuang, Feng Juling, Sun Yan, Huang Xingxu, Lu Karen H, Li Zheng
Format: Article
Language:English
Published: BMC 2010-09-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/244