Synthesis, Characterization, Acetylcholinesterase Inhibition, Molecular Modeling and Antioxidant Activities of Some Novel Schiff Bases Derived from 1-(2-Ketoiminoethyl)piperazines

Synthesis, Characterization, Acetylcholinesterase Inhibition, Molecular Modeling and Antioxidant Activities of Some Novel Schiff Bases Derived from 1-(2-Ketoiminoethyl)piperazines

Some novel Schiff bases derived from 1-(2-ketoiminoethyl)piperazines were synthesized and characterized by mass spectroscopy, FTIR, UV-Visible, 1H and 13C-NMR. The compounds were tested for inhibitory activities on human acetylcholinesterase (hAChE), antioxidant activities, acute oral toxicity and f...

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Bibliographic Details
Main Authors: A. Hamid A. Hadi, Sri Devi Sukumaran, Michael J. C. Buckle, Lam Kok Wai, Siddig I. Abdelwahab, Mahmood A. Abdullah, Hapipah M. Ali, Saleh M. Salga
Format: Article
Language:English
Published: MDPI AG 2011-11-01
Series:Molecules
Subjects:
1-(2-ketoiminoethyl)piperazines
AChE inhibition
molecular docking
antioxidant study
acute toxicity
Online Access:http://www.mdpi.com/1420-3049/16/11/9316/

Internet

http://www.mdpi.com/1420-3049/16/11/9316/

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