Beneficial role of rapamycin in experimental autoimmune myositis.

We developed an experimental autoimmune myositis (EAM) mouse model of polymyositis where we outlined the role of regulatory T (Treg) cells. Rapamycin, this immunosuppressant drug used to prevent rejection in organ transplantation, is known to spare Treg. Our aim was to test the efficacy of rapamycin...

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Bibliographic Details
Main Authors: Nicolas Prevel, Yves Allenbach, David Klatzmann, Benoit Salomon, Olivier Benveniste
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827074?pdf=render