A Systematic Review on the Existing Screening Pathways for Lynch Syndrome Identification

A Systematic Review on the Existing Screening Pathways for Lynch Syndrome Identification

BackgroundLynch syndrome (LS) is the most common hereditary colon cancer syndrome, accounting for 3–5% of colorectal cancer (CRC) cases, and it is associated with the development of other cancers. Early detection of individuals with LS is relevant, since they can take advantage of life-saving intens...

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Bibliographic Details
Main Authors: Alessia Tognetto, Maria Benedetta Michelazzo, Giovanna Elisa Calabró, Brigid Unim, Marco Di Marco, Walter Ricciardi, Roberta Pastorino, Stefania Boccia
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Public Health
Subjects:
colorectal cancer
hereditary colorectal cancer
Lynch syndrome
immunohistochemistry
microsatellite instability
mismatch repair genes
Online Access:http://journal.frontiersin.org/article/10.3389/fpubh.2017.00243/full

Internet

http://journal.frontiersin.org/article/10.3389/fpubh.2017.00243/full

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