Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.

Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.

Pseudomonas aeruginosa is an opportunistic human pathogen that is a key factor in the mortality of cystic fibrosis patients, and infection represents an increased threat for human health worldwide. Because resistance of Pseudomonas aeruginosa to antibiotics is increasing, new inhibitors of pharmacol...

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Bibliographic Details
Main Authors: Anthony Arnoldo, Jasna Curak, Saranya Kittanakom, Igor Chevelev, Vincent T Lee, Mehdi Sahebol-Amri, Becky Koscik, Lana Ljuma, Peter J Roy, Antonio Bedalov, Guri Giaever, Corey Nislow, A Rod Merrill, Stephen Lory, Igor Stagljar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-02-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2265467?pdf=render

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http://europepmc.org/articles/PMC2265467?pdf=render

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