MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects.

Recent studies suggest that alterations in expression of genes, including those which regulate neural and structural plasticity, may be crucial in the pathogenesis of depression. MicroRNAs (miRNAs) are newly discovered regulators of gene expression that have recently been implicated in a variety of...

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Bibliographic Details
Main Authors: Neil R Smalheiser, Giovanni Lugli, Hooriyah S Rizavi, Vetle I Torvik, Gustavo Turecki, Yogesh Dwivedi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3302855?pdf=render