Synthesis of some pyrazolone derivatives from ciprofloxacin and study of their cytotoxicity

Three pyrazolone derivatives with pyrazole ring extension were synthesized from ciprofloxacin by treating the parent compound with hydrazine derivatives. All the products have been characterized by IR and 1H-NMR spectral analysis. These derivatives showed potential cytotoxicity against brine shrimp...

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Bibliographic Details
Main Authors: Hari Pado Devnath, Md. Rabiul Islam
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2010-06-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:http://www.banglajol.info/index.php/BJP/article/view/4693/4095