Rare Germline Variants in Chordoma-Related Genes and Chordoma Susceptibility

Rare Germline Variants in Chordoma-Related Genes and Chordoma Susceptibility

Background: Chordoma is a rare bone cancer with an unknown etiology. TBXT is the only chordoma susceptibility gene identified to date; germline single nucleotide variants and copy number variants in TBXT have been associated with chordoma susceptibility in familial and sporadic chordoma. However, th...

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Bibliographic Details
Main Authors: Sally Yepes, Nirav N. Shah, Jiwei Bai, Hela Koka, Chuzhong Li, Songbai Gui, Mary Lou McMaster, Yanzi Xiao, Kristine Jones, Mingyi Wang, Aurelie Vogt, Bin Zhu, Amy Hutchinson, Meredith Yeager, Belynda Hicks, Brian Carter, Neal D. Freedman, Laura Beane-Freeman, Stephen J. Chanock, Yazhuo Zhang, Dilys M. Parry, Xiaohong R. Yang, Alisa M. Goldstein
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
chordoma
germline variants
notochord development
cancer susceptibility
WES
WGS
Online Access:https://www.mdpi.com/2072-6694/13/11/2704

Internet

https://www.mdpi.com/2072-6694/13/11/2704

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