Efficacy of a marine bacterial nuclease against biofilm forming microorganisms isolated from chronic rhinosinusitis.

<h4>Background</h4>The persistent colonization of paranasal sinus mucosa by microbial biofilms is a major factor in the pathogenesis of chronic rhinosinusitis (CRS). Control of microorganisms within biofilms is hampered by the presence of viscous extracellular polymers of host or microbi...

Full description

Bibliographic Details
Main Authors: Robert C Shields, Norehan Mokhtar, Michael Ford, Michael J Hall, J Grant Burgess, Mohamed Reda ElBadawey, Nicholas S Jakubovics
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23441151/?tool=EBI