Scavenger receptors mediate the role of SUMO and Ftz-f1 in Drosophila steroidogenesis.

SUMOylation participates in ecdysteroid biosynthesis at the onset of metamorphosis in Drosophila melanogaster. Silencing the Drosophila SUMO homologue smt3 in the prothoracic gland leads to reduced lipid content, low ecdysone titers, and a block in the larval-pupal transition. Here we show that the...

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Bibliographic Details
Main Authors: Ana Talamillo, Leire Herboso, Lucia Pirone, Coralia Pérez, Monika González, Jonatan Sánchez, Ugo Mayor, Fernando Lopitz-Otsoa, Manuel S Rodriguez, James D Sutherland, Rosa Barrio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3630131?pdf=render