Micro-MRI study of cerebral aging: ex vivo detection of hippocampal subfield reorganization, microhemorrhages and amyloid plaques in mouse lemur primates.

Mouse lemurs are non-human primate models of cerebral aging and neurodegeneration. Much smaller than other primates, they recapitulate numerous features of human brain aging, including progressive cerebral atrophy and correlation between regional atrophy and cognitive impairments. Characterization o...

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Bibliographic Details
Main Authors: Anne Bertrand, Adrien Pasquier, Alexandra Petiet, Christopher Wiggins, Audrey Kraska, Nelly Joseph-Mathurin, Fabienne Aujard, Nadine Mestre-Francés, Marc Dhenain
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3584101?pdf=render