Lycopene and beta-carotene induce growth inhibition and proapoptotic effects on ACTH-secreting pituitary adenoma cells.

Lycopene and beta-carotene induce growth inhibition and proapoptotic effects on ACTH-secreting pituitary adenoma cells.

Pituitary adenomas comprise approximately 10-15% of intracranial tumors and result in morbidity associated with altered hormonal patterns, therapy and compression of adjacent sella turcica structures. The use of functional foods containing carotenoids contributes to reduce the risk of chronic diseas...

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Bibliographic Details
Main Authors: Natália F Haddad, Anderson J Teodoro, Felipe Leite de Oliveira, Nathália Soares, Rômulo Medina de Mattos, Fábio Hecht, Rômulo Sperduto Dezonne, Leandro Vairo, Regina Coeli Dos Santos Goldenberg, Flávia Carvalho Alcântara Gomes, Denise Pires de Carvalho, Mônica R Gadelha, Luiz Eurico Nasciutti, Leandro Miranda-Alves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3647049?pdf=render

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http://europepmc.org/articles/PMC3647049?pdf=render

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