Exonuclease III-Regulated Target Cyclic Amplification-Based Single Nucleotide Polymorphism Detection Using Ultrathin Ternary Chalcogenide Nanosheets

Exonuclease III-Regulated Target Cyclic Amplification-Based Single Nucleotide Polymorphism Detection Using Ultrathin Ternary Chalcogenide Nanosheets

Herein, we report that the ternary chalcogenide nanosheet exhibits different affinity toward oligonucleotides with different lengths and efficiently quenches the fluorescence of dye-labeled DNA probes. Based on these findings, as a proof-of-concept application, the ternary chalcogenide nanosheet is...

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Bibliographic Details
Main Authors: Yanling Hu, Chaoliang Tan, Xin Lin, Zhuangchai Lai, Xiao Zhang, Qipeng Lu, Ning Feng, Dongliang Yang, Lixing Weng
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Chemistry
Subjects:
ternary chalcogenide nanosheets
single nucleotide polymorphisms
two-dimensional nanomaterials
fluorescent detection
sensor
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00844/full

Internet

https://www.frontiersin.org/article/10.3389/fchem.2019.00844/full

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