Epithelial heparan sulfate regulates Sonic Hedgehog signaling in lung development.

The tree-like structure of the mammalian lung is generated from branching morphogenesis, a reiterative process that is precisely regulated by numerous factors. How the cell surface and extra cellular matrix (ECM) molecules regulate this process is still poorly understood. Herein, we show that epithe...

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Bibliographic Details
Main Authors: Hua He, Meina Huang, Shenfei Sun, Yihui Wu, Xinhua Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5597256?pdf=render