Comparative Study of Chemical Stability of Two H1 Antihistaminic Drugs, Terfenadine and Its In Vivo Metabolite Fexofenadine, Using LC-UV Methods

A comparative study of chemical stability of terfenadine (TER) and its in vivo metabolite fexofenadine (FEX) was performed. Both TER and FEX were subjected to high temperature at different pH and UV/VIS light at different pH and then quantitatively analyzed using new validated LC-UV methods. These m...

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Bibliographic Details
Main Authors: Anna Gumieniczek, Anna Berecka-Rycerz, Rafał Pietraś, Izabela Kozak, Karolina Lejwoda, Paweł Kozyra
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2019/5790404