Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments

<p>Abstract</p> <p>Background</p> <p>Progressive loss of articular cartilage is a central hallmark in many joint disease, however, the relative importance of individual proteolytic pathways leading to cartilage erosion is at present unknown. We therefore investigated th...

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Bibliographic Details
Main Authors: Sondergaard Bodil-Cecilie, Madsen Suzi H, Karsdal Morten A, Jensen Anne-Christine, Chen Pingping, Wang Bijue, Zheng Qinlong, Qvist Per
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/2/259