Trisomy 8, a Cytogenetic Abnormality in Myelodysplastic Syndromes, Is Constitutional or Not?

Trisomy 8, a Cytogenetic Abnormality in Myelodysplastic Syndromes, Is Constitutional or Not?

Isolated trisomy 8 is not considered presumptive evidence of myelodysplastic syndrome (MDS) in cases without minimal morphological criteria. One reason given is that trisomy 8 (+8) can be found as a constitutional mosaicism (cT8M). We tried to clarify the incidence of cT8M in myeloid neoplasms, spec...

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Bibliographic Details
Main Authors: Sílvia Saumell, Francesc Solé, Leonor Arenillas, Julia Montoro, David Valcárcel, Carme Pedro, Carmen Sanzo, Elisa Luño, Teresa Giménez, Montserrat Arnan, Helena Pomares, Raquel De Paz, Beatriz Arrizabalaga, Andrés Jerez, Ana B Martínez, Judith Sánchez-Castro, Juan D Rodríguez-Gambarte, José M Raya, Eduardo Ríos, María Rodríguez-Rivera, Blanca Espinet, Lourdes Florensa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4466575?pdf=render

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http://europepmc.org/articles/PMC4466575?pdf=render

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