Importance of A-loop complementarity with tRNA<sup>His </sup>anticodon for continued selection of tRNA<sup>His </sup>as the HIV reverse transcription primer
<p>Abstract</p> <p>Background</p> <p>Human immunodeficiency virus (HIV-1) preferentially selects tRNA<sup>Lys,3 </sup>as the primer for reverse transcription. HIV-1 can be forced to select alternative tRNAs through mutation in the primer-binding site (PBS) a...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-01-01
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| Series: | Virology Journal |
| Online Access: | http://www.virologyj.com/content/4/1/4 |