Disordering of human telomeric G-quadruplex with novel antiproliferative anthrathiophenedione.

Disordering of human telomeric G-quadruplex with novel antiproliferative anthrathiophenedione.

Linear heteroareneanthracenediones have been shown to interfere with DNA functions, thereby causing death of human tumor cells and their drug resistant counterparts. Here we report the interaction of our novel antiproliferative agent 4,11-bis[(2-{[acetimido]amino}ethyl)amino]anthra[2,3-b]thiophene-5...

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Main Authors: Dmitry Kaluzhny, Nikolay Ilyinsky, Andrei Shchekotikhin, Yuri Sinkevich, Philipp O Tsvetkov, Vladimir Tsvetkov, Alexander Veselovsky, Mikhail Livshits, Olga Borisova, Alexander Shtil, Anna Shchyolkina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3216923?pdf=render

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http://europepmc.org/articles/PMC3216923?pdf=render

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