Anthocyanin-rich bilberry extract induces apoptosis in acute lymphoblastic leukemia cells via redox-sensitive epigenetic modifications

Polycomb group (PcG) proteins are epigenetic regulators that reduce tumor suppressor gene expression and promote cancer cell survival. The aim of the present study was to determine whether a bilberry extract (Antho 50) inhibits the expression of PcG proteins in Jurkat cells and, if so, to determine...

Full description

Bibliographic Details
Main Authors: Antonio J. León-González, Tanveer Sharif, Cyril Auger, Malak Abbas, Guy Fuhrmann, Valérie B. Schini-Kerth
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Journal of Functional Foods
Subjects:
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618300999