Polymer-Encapsulated PC-12 Cells Demonstrate High-Affinity Uptake of Dopamine in Vitro and F-DOPA Uptake and Metabolism after Intracerebral Implantation in Nonhuman Primates

Polymer-Encapsulated PC-12 Cells Demonstrate High-Affinity Uptake of Dopamine in Vitro and F-DOPA Uptake and Metabolism after Intracerebral Implantation in Nonhuman Primates

Intracranial implantation of polymer-encapsulated PC-12 cells has been shown to improve motor behavioral performance in animal models of Parkinson's disease. The purpose of this blinded study was to examine whether such improvement is associated with the active uptake and metabolism of dopamine...

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Bibliographic Details
Main Authors: Thyagarajan Subramanian M.D., Dwaine F. Emerich, Roy A. E. Bakay, John M. Hoffman, Mark M. Goodman, Timothy M. Shoup, Gary W. Miller, Allan I. Levey, George W. Hubert, Scott Batchelor, Shelly R. Winn, Joel A. Saydoff, Ray L. Watts
Format: Article
Language:English
Published: SAGE Publishing 1997-09-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368979700600506

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https://doi.org/10.1177/096368979700600506

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