Age Influences Microglial Activation After Cuprizone-Induced Demyelination

Age Influences Microglial Activation After Cuprizone-Induced Demyelination

Multiple sclerosis (MS) is a chronic inflammatory CNS disease, which causes demyelinated lesions and damages white and gray matter regions. Aging is a significant factor in the progression of MS, and microglia, the immune cells of the CNS tissue, play an important role in all disease stages. During...

Full description

Bibliographic Details
Main Authors: Barbara Klein, Heike Mrowetz, Conor Michael Barker, Simona Lange, Francisco J. Rivera, Ludwig Aigner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
microglia
aging
demyelination
cuprizone
hippocampus
corpus callosum
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2018.00278/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2018.00278/full

Similar Items