Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury.

Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury.

Infiltrating monocyte-derived macrophages (MDMs) and resident microglia dominate central nervous system (CNS) injury sites. Differential roles for these cell populations after injury are beginning to be uncovered. Here, we show evidence that MDMs and microglia directly communicate with one another a...

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Bibliographic Details
Main Authors: Andrew D Greenhalgh, Juan G Zarruk, Luke M Healy, Sam J Baskar Jesudasan, Priya Jhelum, Christopher K Salmon, Albert Formanek, Matthew V Russo, Jack P Antel, Dorian B McGavern, Barry W McColl, Samuel David
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2005264

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https://doi.org/10.1371/journal.pbio.2005264

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