Paraoxonase-1 status in patients with hereditary hemochromatosis

Paraoxonase-1 status in patients with hereditary hemochromatosis

Hereditary hemochromatosis (HH) is characterized by accumulation of iron, oxidative stress, inflammation, and fibrogenesis in liver tissue. In this setting, research on the protection afforded by intracellular antioxidants is of clinical relevance. Paraoxonase-1 (PON1) is an enzyme that degrades lip...

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Bibliographic Details
Main Authors: Nicola Martinelli, Anabel García-Heredia, Helena Roca, Núria Aranda, Victoria Arija, Bharti Mackness, Michael Mackness, Fabiana Busti, Gerard Aragonès, Juan Pedro-Botet, Federica Pedica, Ivana Cataldo, Judit Marsillach, Jorge Joven, Domenico Girelli, Jordi Camps
Format: Article
Language:English
Published: Elsevier 2013-05-01
Series:Journal of Lipid Research
Subjects:
antioxidants
inflammation
iron metabolism
oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520421856

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http://www.sciencedirect.com/science/article/pii/S0022227520421856

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