Transcription factor Krüppel-like factor 5-regulated N-myc downstream-regulated gene 2 reduces IL-1β-induced chondrocyte inflammatory injury and extracellular matrix degradation

Transcription factor Krüppel-like factor 5-regulated N-myc downstream-regulated gene 2 reduces IL-1β-induced chondrocyte inflammatory injury and extracellular matrix degradation

Previous research has identified N-myc downstream-regulated gene 2 (NDRG2) as one of the differentially expressed genes common to rat models of osteoarthritis (OA) and human OA. The purpose of this study was to investigate the role of NDRG2 in OA. In this study, an in vitro OA model was constructed...

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Bibliographic Details
Main Authors: Xiaoliang Mei, Hao Din, Jianning Zhao, Jian Tong, Wei Zhu
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Bioengineered
Subjects:
osteoarthritis
ndrg2
chondrocyte apoptosis
inflammatory response
extracellular matrix degradation
Online Access:http://dx.doi.org/10.1080/21655979.2021.1971483

Internet

http://dx.doi.org/10.1080/21655979.2021.1971483

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