Propoxyphene Mediates Oxyhemoglobin-Induced Injury in Rat Cortical Neurons Through Up-Regulation of Active-β-Catenin

Propoxyphene Mediates Oxyhemoglobin-Induced Injury in Rat Cortical Neurons Through Up-Regulation of Active-β-Catenin

Wnt/β-catenin signaling is involved in various biological processes, including the development of the central nervous system. The dysfunction of mitochondria has been shown to participate in the progress of subarachnoid hemorrhage (SAH). Traumatic subarachnoid hemorrhage (tSAH) is a serious complica...

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Bibliographic Details
Main Authors: Yuqian Li, Jiancai Wang, Zhihong Li, Hongyu Cheng, Zhuo Zhang, Tao Luo, Xingye Zhang, Guodong Gao, Huashan Lu, Lihong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Pharmacology
Subjects:
Propoxyphene
active-β-catenin
apoptosis
traumatic subarachnoid hemorrhage
mitochondrial
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01616/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01616/full

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