Prevention of Elevation in Plasma Triacylglycerol with High-Dose Bezafibrate Treatment Abolishes Insulin Resistance and Attenuates Glucose Intolerance Induced by Short-Term Treatment with Dexamethasone in Rats

Objective. Fibrates are used as lipid-lowering drugs and are well tolerated as cotreatments when glucose metabolism disturbances are also present. Synthetic glucocorticoids (GCs) are diabetogenic drugs that cause dyslipidemia, dysglycemia, glucose intolerance, and insulin resistance when in excess....

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Bibliographic Details
Main Authors: Maiara Destro Inácio, Alex Rafacho, Nathália Aparecida de Paula Camaforte, Poliana Teixeira, Priscilla Maria Ponce Vareda, Natália Moretti Violato, José Roberto Bosqueiro
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2018/3257812