A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo

Directed differentiation of pluripotent stem cells provides an accessible system to model development. However, the distinct cell types that emerge, their dynamics, and their relationship to progenitors in the early embryo has been difficult to decipher because of the cellular heterogeneity inherent...

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Bibliographic Details
Main Authors: Abby Spangler, Emily Y. Su, April M. Craft, Patrick Cahan
Format: Article
Language:English
Published: Elsevier 2018-08-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506118301909