Adjusting breast cancer patient prognosis with non-HER2-gene patterns on chromosome 17.

BACKGROUND: HER2 and TOP2A gene status are assessed for diagnostic and research purposes in breast cancer with fluorescence in situ hybridization (FISH). However, FISH probes do not target only the annotated gene, while chromosome 17 (chr17) is among the most unstable chromosomes in breast cancer. H...

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Bibliographic Details
Main Authors: Vassiliki Kotoula, Mattheos Bobos, Zoi Alexopoulou, Christos Papadimitriou, Kyriaki Papadopoulou, Elpida Charalambous, Eleftheria Tsolaki, Grigorios Xepapadakis, Irene Nicolaou, Irene Papaspirou, Gerasimos Aravantinos, Christos Christodoulou, Ioannis Efstratiou, Helen Gogas, George Fountzilas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4123879?pdf=render