Cyclic AMP Regulates Key Features of Macrophages via PKA: Recruitment, Reprogramming and Efferocytosis

Cyclic AMP Regulates Key Features of Macrophages via PKA: Recruitment, Reprogramming and Efferocytosis

Macrophages are central to inflammation resolution, an active process aimed at restoring tissue homeostasis following an inflammatory response. Here, the effects of db-cAMP on macrophage phenotype and function were investigated. Injection of db-cAMP into the pleural cavity of mice induced monocytes...

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Bibliographic Details
Main Authors: Graziele L. Negreiros-Lima, Kátia M. Lima, Isabella Z. Moreira, Bruna Lorrayne O. Jardim, Juliana P. Vago, Izabela Galvão, Lívia Cristina R. Teixeira, Vanessa Pinho, Mauro M. Teixeira, Michelle A. Sugimoto, Lirlândia P. Sousa
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
inflammation resolution
db-camp
macrophage recruitment
macrophage reprogramming
efferocytosis
Online Access:https://www.mdpi.com/2073-4409/9/1/128

Internet

https://www.mdpi.com/2073-4409/9/1/128

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