Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease

Reduced Lysosomal Acid Lipase Activity in Adult Patients With Non-alcoholic Fatty Liver Disease

Non-alcoholic fatty liver disease (NAFLD) is characterized by intra-hepatic fat accumulation and mechanisms involved in its pathogenesis are not fully explained. Lysosomal Acid Lipase (LAL) is a key enzyme in lipid metabolism. We investigated its activity in patients with fatty liver. LAL activity (...

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Bibliographic Details
Main Authors: Francesco Baratta, Daniele Pastori, Maria Del Ben, Licia Polimeni, Giancarlo Labbadia, Serena Di Santo, Fiorella Piemonte, Giulia Tozzi, Francesco Violi, Francesco Angelico
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:EBioMedicine
Subjects:
Lysosomal acid lipase
Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Metabolic syndrome
Statins
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415300232

Internet

http://www.sciencedirect.com/science/article/pii/S2352396415300232

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