Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin

Phenethyl Isothiocyanate Suppresses Stemness in the Chemo- and Radio-Resistant Triple-Negative Breast Cancer Cell Line MDA-MB-231/IR Via Downregulation of Metadherin

Resistance to chemotherapy and radiation therapy is considered a major therapeutic barrier in breast cancer. Cancer stem cells (CSCs) play a prominent role in chemo and radiotherapy resistance. The established chemo and radio-resistant triple-negative breast cancer (TNBC) cell line MDA-MB-231/IR dis...

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Bibliographic Details
Main Authors: Yen Thi-Kim Nguyen, Jeong Yong Moon, Meran Keshawa Ediriweera, Somi Kim Cho
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
phenethyl isothiocyanate
metadherin
cancer stem cells
resistance
reactive oxygen species
Online Access:https://www.mdpi.com/2072-6694/12/2/268

Internet

https://www.mdpi.com/2072-6694/12/2/268

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