CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation
Abstract Background The reported antitumor activity of the BET family bromodomain inhibitors has prompted the development of inhibitors against other bromodomains. However, the human genome encodes more than 60 different bromodomains and most of them remain unexplored. Results We report that the bro...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-06-01
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Series: | Epigenetics & Chromatin |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13072-018-0197-x |