Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cellsResearch in Context

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cellsResearch in Context

Background: While smoking is known to associate with development of multiple diseases, the underlying mechanisms are still poorly understood. Tobacco smoking can modify the chemical integrity of DNA leading to changes in transcriptional activity, partly through an altered epigenetic state. We aimed...

Full description

Bibliographic Details
Main Authors: Mikael V. Ringh, Michael Hagemann-Jensen, Maria Needhamsen, Lara Kular, Charles E. Breeze, Louise K. Sjöholm, Lara Slavec, Susanna Kullberg, Jan Wahlström, Johan Grunewald, Boel Brynedal, Yun Liu, Malin Almgren, Maja Jagodic, Johan Öckinger, Tomas J. Ekström
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304414

Internet

http://www.sciencedirect.com/science/article/pii/S2352396419304414

Similar Items