Frequency of the LRRK2 G2019S mutation in late-onset sporadic patients with Parkinson’s disease

Mutations in the LRRK2 gene, predominantly G2019S, have been reported in individuals with autosomal dominant inheritance and sporadic Parkinson’s disease (PD). The G2019S mutation has an age-dependent penetrance and evidence shows common ancestry. The clinical manifestations are indistinguishable fr...

Full description

Bibliographic Details
Main Authors: Hsin Fen Chien, Tamires Rocha Figueiredo, Marianna Almeida Hollaender, Fabiano Tofoli, Leonel Takao Takada, Lygia da Veiga Pereira, Egberto Reis Barbosa
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2014-05-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2014000500356&lng=en&tlng=en