Going beyond Integration: The Emerging Role of HIV-1 Integrase in Virion Morphogenesis

The HIV-1 integrase enzyme (IN) plays a critical role in the viral life cycle by integrating the reverse-transcribed viral DNA into the host chromosome. This function of IN has been well studied, and the knowledge gained has informed the design of small molecule inhibitors that now form key componen...

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Bibliographic Details
Main Authors: Jennifer L. Elliott, Sebla B. Kutluay
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/9/1005