Importance of TLR2 on hepatic immune and non-immune cells to attenuate the strong inflammatory liver response during Trypanosoma cruzi acute infection.

Importance of TLR2 on hepatic immune and non-immune cells to attenuate the strong inflammatory liver response during Trypanosoma cruzi acute infection.

BACKGROUND: Toll-like receptors (TLR) and cytokines play a central role in the pathogen clearance as well as in pathological processes. Recently, we reported that TLR2, TLR4 and TLR9 are differentially modulated in injured livers from BALB/c and C57BL/6 (B6) mice during Trypanosoma cruzi infection....

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Bibliographic Details
Main Authors: Eugenio Antonio Carrera-Silva, Natalia Guiñazu, Andrea Pellegrini, Roxana Carolina Cano, Alfredo Arocena, Maria Pilar Aoki, Susana Gea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2970533?pdf=render

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http://europepmc.org/articles/PMC2970533?pdf=render

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