Decreased Proliferation in the Neurogenic Niche, Disorganized Neuroblast Migration, and Increased Oligodendrogenesis in Adult Netrin-5-Deficient Mice

Decreased Proliferation in the Neurogenic Niche, Disorganized Neuroblast Migration, and Increased Oligodendrogenesis in Adult Netrin-5-Deficient Mice

In the adult mouse brain, neurogenesis occurs mainly in the ventricular-subventricular zone (V-SVZ) and the subgranular zone of the hippocampal dentate gyrus. Neuroblasts generated in the V-SVZ migrate to the olfactory bulb via the rostral migratory stream (RMS) in response to guidance molecules, su...

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Bibliographic Details
Main Authors: Shunsuke Ikegaya, Yurika Iga, Sumiko Mikawa, Li Zhou, Manabu Abe, Kenji Sakimura, Kohji Sato, Satoru Yamagishi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neuroscience
Subjects:
adult neurogenesis
axon guidance
netrin
subventricular zone
oligodendrogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.570974/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2020.570974/full

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