Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes

Evaluation of Trichodysplasia Spinulosa-Associated Polyomavirus Capsid Protein as a New Carrier for Construction of Chimeric Virus-Like Particles Harboring Foreign Epitopes

Recombinant virus-like particles (VLPs) represent a promising tool for protein engineering. Recently, trichodysplasia spinulosa-associated polyomavirus (TSPyV) viral protein 1 (VP1) was efficiently produced in yeast expression system and shown to self-assemble to VLPs. In the current study, TSPyV VP...

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Bibliographic Details
Main Authors: Alma Gedvilaite, Indre Kucinskaite-Kodze, Rita Lasickiene, Albertas Timinskas, Ausra Vaitiekaite, Danguole Ziogiene, Aurelija Zvirbliene
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Viruses
Subjects:
Chimeric virus-like particles
polyomaviruses
TSPyV VP1 protein
immunogenicity
Online Access:http://www.mdpi.com/1999-4915/7/8/2818

Internet

http://www.mdpi.com/1999-4915/7/8/2818

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