Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer

Estrogen-induced miR-196a elevation promotes tumor growth and metastasis via targeting SPRED1 in breast cancer

Abstract Background Estrogen plays a critical role in breast cancer (BC) progression through estrogen receptor (ER)-mediated gene regulation. Emerging studies suggest that the malignant progress of BC cells is influenced by the cross talk between microRNAs (miRNAs) and ER-α signaling. However, the m...

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Bibliographic Details
Main Authors: Cheng-Fei Jiang, Zhu-Mei Shi, Dong-Mei Li, Ying-Chen Qian, Yi Ren, Xiao-Ming Bai, Yun-Xia Xie, Lin Wang, Xin Ge, Wei-Tao Liu, Lin-Lin Zhen, Ling-Zhi Liu, Bing-Hua Jiang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Molecular Cancer
Subjects:
Estrogen
miR-196a
SPRED1
Breast cancer
Estrogen receptors
Online Access:http://link.springer.com/article/10.1186/s12943-018-0830-0

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http://link.springer.com/article/10.1186/s12943-018-0830-0

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