Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo.

Helicobacter pylori is the strongest known risk factor for the development of gastric adenocarcinoma. H. pylori expresses a repertoire of virulence factors that increase gastric cancer risk, including the cag pathogenicity island and the vacuolating cytotoxin (VacA). One host element that promotes c...

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Bibliographic Details
Main Authors: Jennifer M Noto, Tinatin Khizanishvili, Rupesh Chaturvedi, M Blanca Piazuelo, Judith Romero-Gallo, Alberto G Delgado, Shradha S Khurana, Johanna C Sierra, Uma S Krishna, Giovanni Suarez, Anne E Powell, James R Goldenring, Robert J Coffey, Vincent W Yang, Pelayo Correa, Jason C Mills, Keith T Wilson, Richard M Peek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553174?pdf=render