Pathway analysis with genome-wide association study (GWAS) data detected the association of atrial fibrillation with the mTOR signaling pathway

Background: Genome-wide association studies (GWAS) have identified numerous loci associated with diseases and traits. However, the elucidation of disease mechanisms followed by drug development has remained a challenge owing to complex gene interactions. We performed pathway analysis with MAGENTA (M...

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Bibliographic Details
Main Authors: Yusuke Ebana, Yihan Sun, Xiaoxi Yang, Taiju Watanabe, Satoru Makita, Kouichi Ozaki, Toshihiro Tanaka, Hirokuni Arai, Tetsushi Furukawa
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:International Journal of Cardiology: Heart & Vasculature
Online Access:http://www.sciencedirect.com/science/article/pii/S2352906719300880