The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

Our knowledge about the repertoire of ribosomal RNA modifications and the enzymes responsible for installing them is constantly expanding. Previously, we reported that NSUN-5 is responsible for depositing m5C at position C2381 on the 26S rRNA in Caenorhabditis elegans. Here, we show that NSUN-1 is w...

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Bibliographic Details
Main Authors: Clemens Heissenberger, Jarod A Rollins, Teresa L Krammer, Fabian Nagelreiter, Isabella Stocker, Ludivine Wacheul, Anton Shpylovyi, Koray Tav, Santina Snow, Johannes Grillari, Aric N Rogers, Denis L J Lafontaine, Markus Schosserer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-12-01
Series:eLife
Subjects:
aging
RNA methylation
ribosome
translation
nsun1/nop2/p120
nsun5/rcm1
Online Access:https://elifesciences.org/articles/56205

Internet

https://elifesciences.org/articles/56205

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