Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein

Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein

Abstract Background Ischemia/reperfusion injury (I/R) is an important pathophysiology of post-cardiac arrest syndrome (PCAS) against multiple organ dysfunction and mortality. The inflammatory response in PCAS causes systemic I/R. The purpose of this study was to demonstrate the pathophysiology of sy...

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Bibliographic Details
Main Authors: Atsunori Sugita, Kosaku Kinoshita, Atsushi Sakurai, Nobutaka Chiba, Junko Yamaguchi, Tsukasa Kuwana, Nami Sawada, Satoshi Hori
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Critical Care
Subjects:
HMGB1
IL-6
NSE
SOFA score
Post-cardiac arrest syndrome
Systemic ischemia/reperfusion injury
Online Access:http://link.springer.com/article/10.1186/s13054-017-1828-5

Internet

http://link.springer.com/article/10.1186/s13054-017-1828-5

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