Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.

Helicobacter pylori CagA triggers expression of the bactericidal lectin REG3γ via gastric STAT3 activation.

BACKGROUND: Most of what is known about the Helicobacter pylori (H. pylori) cytotoxin, CagA, pertains to a much-vaunted role as a determinant of gastric inflammation and cancer. Little attention has been devoted to potential roles of CagA in the majority of H. pylori infected individuals not showing...

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Bibliographic Details
Main Authors: Kai Syin Lee, Anastasia Kalantzis, Cameron B Jackson, Louise O'Connor, Naoko Murata-Kamiya, Masanori Hatakeyama, Louise M Judd, Andrew S Giraud, Trevelyan R Menheniott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3270022?pdf=render

Internet

http://europepmc.org/articles/PMC3270022?pdf=render

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